| Grundserie | Ma | +/- | P | |||||||
| 1 | Philadelphia Union | 5 | 4 | 12 | 2 | 4 | 6 | 7 | 8 | 18 |
| 2 | Charlotte FC | 5 | 13 | 15 | 2 | -1 | 1 | 7 | 12 | 16 |
| 3 | Chicago Fire | 1 | 0 | 1 | 4 | 3 | 9 | 5 | 3 | 10 |
| 4 | Inter Miami | 2 | 1 | 4 | 2 | 4 | 6 | 4 | 5 | 10 |
| 5 | Nashville | 3 | 5 | 7 | 2 | 0 | 3 | 5 | 5 | 10 |
| 6 | Columbus Crew | 3 | 2 | 5 | 2 | 1 | 4 | 5 | 3 | 9 |
| 7 | New York City FC | 2 | 2 | 6 | 3 | -1 | 2 | 5 | 1 | 8 |
| 8 | New York Red Bulls | 3 | 3 | 7 | 2 | -1 | 1 | 5 | 2 | 8 |
| 9 | FC Cincinnati | 3 | 3 | 7 | 2 | -5 | 0 | 5 | -2 | 7 |
| 10 | Orlando City | 3 | 3 | 6 | 2 | -1 | 1 | 5 | 2 | 7 |
| 11 | DC United | 3 | 1 | 5 | 2 | -3 | 1 | 5 | -2 | 6 |
| 12 | Atlanta United | 3 | 0 | 4 | 2 | -2 | 1 | 5 | -2 | 5 |
| 13 | CF Montréal | 0 | 0 | 0 | 5 | -7 | 1 | 5 | -7 | 1 |
| 14 | New England Revolution | 2 | -3 | 0 | 2 | -1 | 1 | 4 | -4 | 1 |
| 15 | Toronto FC | 1 | -1 | 0 | 4 | -5 | 1 | 5 | -6 | 1 |
| Grundserie | Ma | +/- | P | |||||||
| 1 | Philadelphia Union | 5 | 4 | 12 | 2 | 4 | 6 | 7 | 8 | 18 |
| 2 | Charlotte FC | 5 | 13 | 15 | 2 | -1 | 1 | 7 | 12 | 16 |
| 3 | Chicago Fire | 1 | 0 | 1 | 4 | 3 | 9 | 5 | 3 | 10 |
| 4 | Inter Miami | 2 | 1 | 4 | 2 | 4 | 6 | 4 | 5 | 10 |
| 5 | Nashville | 3 | 5 | 7 | 2 | 0 | 3 | 5 | 5 | 10 |
| 6 | Columbus Crew | 3 | 2 | 5 | 2 | 1 | 4 | 5 | 3 | 9 |
| 7 | New York City FC | 2 | 2 | 6 | 3 | -1 | 2 | 5 | 1 | 8 |
| 8 | New York Red Bulls | 3 | 3 | 7 | 2 | -1 | 1 | 5 | 2 | 8 |
| 9 | FC Cincinnati | 3 | 3 | 7 | 2 | -5 | 0 | 5 | -2 | 7 |
| 10 | Orlando City | 3 | 3 | 6 | 2 | -1 | 1 | 5 | 2 | 7 |
| 11 | DC United | 3 | 1 | 5 | 2 | -3 | 1 | 5 | -2 | 6 |
| 12 | Atlanta United | 3 | 0 | 4 | 2 | -2 | 1 | 5 | -2 | 5 |
| 13 | CF Montréal | 0 | 0 | 0 | 5 | -7 | 1 | 5 | -7 | 1 |
| 14 | New England Revolution | 2 | -3 | 0 | 2 | -1 | 1 | 4 | -4 | 1 |
| 15 | Toronto FC | 1 | -1 | 0 | 4 | -5 | 1 | 5 | -6 | 1 |
| Grundserie | Ma | +/- | P | |||||||
| 1 | Vancouver Whitecaps | 3 | 1 | 6 | 2 | 4 | 6 | 5 | 5 | 12 |
| 2 | Austin FC | 3 | 1 | 6 | 2 | 0 | 3 | 5 | 1 | 9 |
| 3 | Los Angeles FC | 3 | 1 | 6 | 2 | -1 | 3 | 5 | 0 | 9 |
| 4 | Colorado Rapids | 2 | -3 | 1 | 3 | 2 | 7 | 5 | -1 | 8 |
| 5 | Minnesota United | 2 | 1 | 4 | 3 | 0 | 4 | 5 | 1 | 8 |
| 6 | San Diego FC | 2 | 0 | 2 | 3 | 3 | 6 | 5 | 3 | 8 |
| 7 | St. Louis City | 2 | 1 | 4 | 5 | 0 | 4 | 7 | 1 | 8 |
| 8 | FC Dallas | 2 | -3 | 0 | 3 | 2 | 7 | 5 | -1 | 7 |
| 9 | Portland Timbers | 3 | -2 | 4 | 2 | 1 | 3 | 5 | -1 | 7 |
| 10 | Real Salt Lake | 3 | -1 | 3 | 2 | -3 | 3 | 5 | -4 | 6 |
| 11 | San Jose Earthquakes | 3 | 2 | 3 | 4 | -8 | 3 | 7 | -6 | 6 |
| 12 | Seattle Sounders | 3 | 3 | 5 | 2 | -3 | 0 | 5 | 0 | 5 |
| 13 | Houston Dynamo | 3 | -5 | 0 | 2 | 0 | 2 | 5 | -5 | 2 |
| 14 | Los Angeles Galaxy | 2 | -5 | 0 | 3 | -1 | 2 | 5 | -6 | 2 |
| 15 | Sporting Kansas City | 3 | -3 | 1 | 2 | -2 | 0 | 5 | -5 | 1 |
| Grundserie | Ma | +/- | P | |||||||
| 1 | Vancouver Whitecaps | 3 | 1 | 6 | 2 | 4 | 6 | 5 | 5 | 12 |
| 2 | Austin FC | 3 | 1 | 6 | 2 | 0 | 3 | 5 | 1 | 9 |
| 3 | Los Angeles FC | 3 | 1 | 6 | 2 | -1 | 3 | 5 | 0 | 9 |
| 4 | Colorado Rapids | 2 | -3 | 1 | 3 | 2 | 7 | 5 | -1 | 8 |
| 5 | Minnesota United | 2 | 1 | 4 | 3 | 0 | 4 | 5 | 1 | 8 |
| 6 | San Diego FC | 2 | 0 | 2 | 3 | 3 | 6 | 5 | 3 | 8 |
| 7 | St. Louis City | 2 | 1 | 4 | 5 | 0 | 4 | 7 | 1 | 8 |
| 8 | FC Dallas | 2 | -3 | 0 | 3 | 2 | 7 | 5 | -1 | 7 |
| 9 | Portland Timbers | 3 | -2 | 4 | 2 | 1 | 3 | 5 | -1 | 7 |
| 10 | Real Salt Lake | 3 | -1 | 3 | 2 | -3 | 3 | 5 | -4 | 6 |
| 11 | San Jose Earthquakes | 3 | 2 | 3 | 4 | -8 | 3 | 7 | -6 | 6 |
| 12 | Seattle Sounders | 3 | 3 | 5 | 2 | -3 | 0 | 5 | 0 | 5 |
| 13 | Houston Dynamo | 3 | -5 | 0 | 2 | 0 | 2 | 5 | -5 | 2 |
| 14 | Los Angeles Galaxy | 2 | -5 | 0 | 3 | -1 | 2 | 5 | -6 | 2 |
| 15 | Sporting Kansas City | 3 | -3 | 1 | 2 | -2 | 0 | 5 | -5 | 1 |
| Grundserie | Ma | +/- | P | |||||||
| 1 | Philadelphia Union | 5 | 4 | 12 | 2 | 4 | 6 | 7 | 8 | 18 |
| 2 | Charlotte FC | 5 | 13 | 15 | 2 | -1 | 1 | 7 | 12 | 16 |
| 3 | Vancouver Whitecaps | 3 | 1 | 6 | 2 | 4 | 6 | 5 | 5 | 12 |
| 4 | Inter Miami | 2 | 1 | 4 | 2 | 4 | 6 | 4 | 5 | 10 |
| 5 | Nashville | 3 | 5 | 7 | 2 | 0 | 3 | 5 | 5 | 10 |
| 6 | Chicago Fire | 1 | 0 | 1 | 4 | 3 | 9 | 5 | 3 | 10 |
| 7 | Columbus Crew | 3 | 2 | 5 | 2 | 1 | 4 | 5 | 3 | 9 |
| 8 | Austin FC | 3 | 1 | 6 | 2 | 0 | 3 | 5 | 1 | 9 |
| 9 | Los Angeles FC | 3 | 1 | 6 | 2 | -1 | 3 | 5 | 0 | 9 |
| 10 | San Diego FC | 2 | 0 | 2 | 3 | 3 | 6 | 5 | 3 | 8 |
| 11 | New York Red Bulls | 3 | 3 | 7 | 2 | -1 | 1 | 5 | 2 | 8 |
| 12 | Minnesota United | 2 | 1 | 4 | 3 | 0 | 4 | 5 | 1 | 8 |
| 13 | New York City FC | 2 | 2 | 6 | 3 | -1 | 2 | 5 | 1 | 8 |
| 14 | St. Louis City | 2 | 1 | 4 | 5 | 0 | 4 | 7 | 1 | 8 |
| 15 | Colorado Rapids | 2 | -3 | 1 | 3 | 2 | 7 | 5 | -1 | 8 |
| 16 | Orlando City | 3 | 3 | 6 | 2 | -1 | 1 | 5 | 2 | 7 |
| 17 | FC Dallas | 2 | -3 | 0 | 3 | 2 | 7 | 5 | -1 | 7 |
| 18 | Portland Timbers | 3 | -2 | 4 | 2 | 1 | 3 | 5 | -1 | 7 |
| 19 | FC Cincinnati | 3 | 3 | 7 | 2 | -5 | 0 | 5 | -2 | 7 |
| 20 | DC United | 3 | 1 | 5 | 2 | -3 | 1 | 5 | -2 | 6 |
| 21 | Real Salt Lake | 3 | -1 | 3 | 2 | -3 | 3 | 5 | -4 | 6 |
| 22 | San Jose Earthquakes | 3 | 2 | 3 | 4 | -8 | 3 | 7 | -6 | 6 |
| 23 | Seattle Sounders | 3 | 3 | 5 | 2 | -3 | 0 | 5 | 0 | 5 |
| 24 | Atlanta United | 3 | 0 | 4 | 2 | -2 | 1 | 5 | -2 | 5 |
| 25 | Houston Dynamo | 3 | -5 | 0 | 2 | 0 | 2 | 5 | -5 | 2 |
| 26 | Los Angeles Galaxy | 2 | -5 | 0 | 3 | -1 | 2 | 5 | -6 | 2 |
| 27 | New England Revolution | 2 | -3 | 0 | 2 | -1 | 1 | 4 | -4 | 1 |
| 28 | Sporting Kansas City | 3 | -3 | 1 | 2 | -2 | 0 | 5 | -5 | 1 |
| 29 | Toronto FC | 1 | -1 | 0 | 4 | -5 | 1 | 5 | -6 | 1 |
| 30 | CF Montréal | 0 | 0 | 0 | 5 | -7 | 1 | 5 | -7 | 1 |
Columbus Crew spelar sina hemmamatcher på Historic Crew Stadium i Columbus, Ohio som har en publikkapacitet på 24650 personer.
Columbus Crew mötte New York City FC senast i MLS och matchen slutade oavgjort 0-0.
Columbus Crew möter D.C. United härnäst på bortaplan i MLS, med avspark 00:30 den 30/3.
Hemmaarena: Historic Crew Stadium
Kapacitet: 24650
Stad: Columbus, Ohio
Underlag: Gräs
